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Total 20189 results found since Jan 2013.

FGF Receptor Inhibition is Active Against Mesothelioma and Synergizes with Radio- and Chemotherapy.
Conclusions: Our data suggest that the malignant phenotype of mesothelioma cells depends on intact fibroblast growth factor signals, which consequently should be considered as therapeutic targets with a promising chemo- and radio-sensitizing potential. PMID: 25188816 [PubMed - as supplied by publisher]
Source: American Journal of Respiratory and Critical Care Medicine - September 4, 2014 Category: Respiratory Medicine Authors: Schelch K, Hoda MA, Klikovits T, Münzker J, Ghanim B, Wagner C, Garay T, Laszlo V, Setinek U, Dome B, Filipits M, Pirker C, Heffeter P, Selzer E, Tovari J, Torok S, Kenessey I, Holzmann K, Grasl-Kraupp B, Marian B, Klepetko W, Berger W, Hegedus B, Grusch Tags: Am J Respir Crit Care Med Source Type: research

Critical care of patients with cancer
ABSTRACT Answer questions and earn CME/CNE The increasing prevalence of patients living with cancer in conjunction with the rapid progress in cancer therapy will lead to a growing number of patients with cancer who will require intensive care treatment. Fortunately, the development of more effective oncologic therapies, advances in critical care, and improvements in patient selection have led to an increased survival of critically ill patients with cancer. As a consequence, critical care has become an important cornerstone in the continuum of modern cancer care. Although, in many aspects, critical care for patients with ca...
Source: CA: A Cancer Journal for Clinicians - June 26, 2016 Category: Cancer & Oncology Authors: Alexander Shimabukuro‐Vornhagen, Boris Böll, Matthias Kochanek, Éli Azoulay, Michael S. von Bergwelt‐Baildon Tags: Review Article Source Type: research

Invasive Pulmonary Aspergillosis
Semin Respir Crit Care Med 2020; 41: 080-098 DOI: 10.1055/s-0039-3401990Invasive pulmonary aspergillosis (IPA) remains difficult to diagnose and to treat. Most common risk factors are prolonged neutropenia, hematopoietic stem cell or solid organ transplantation, inherited or acquired immunodeficiency, administration of steroids or other immunosuppressive agents including monoclonal antibodies and new small molecules used for cancer therapy. Critically ill patients are also at high risk of IPA. Clinical signs are unspecific. Early computed tomography (CT)-scan identifies the two main aspects, angioinvasive and airway invasi...
Source: Seminars in Respiratory and Critical Care Medicine - January 29, 2020 Category: Respiratory Medicine Authors: Ledoux, Marie-Pierre Guffroy, Blandine Nivoix, Yasmine Simand, C élestine Herbrecht, Raoul Tags: Review Article Source Type: research

The Dangers of Big Corporate Health Care: Deceptive Marketing of Cancer Treatments
A series of articles over the last few months, culminating in an investigative report by Reuters, provided the newest example of what can go wrong when corporations provide direct care to vulnerable patients.  In this case, the vulnerable patients had cancer, and the corporation that provided them care was the Cancer Treatment Centers of America (CTCA).  I will try to go through the case chronologically.As Rueters reported, CTCA "was founded in 1988 by Richard J. Stephenson, who has been chairman ever since."The Founder's Checkered PastA Misdemeanor As Reuters noted,A graduate of Northwestern University Law Schoo...
Source: Health Care Renewal - March 11, 2013 Category: Health Medicine and Bioethics Commentators Tags: deception crime marketing Cancer Treatment Centers of America hospital systems complementary/ alternative medicine Source Type: blogs

Imaging of Drug-Related Pneumonitis in Oncology
This article will describe the computed tomography (CT) pattern-based approach for drug-related pneumonitis that has been utilized to describe the imaging manifestations of pneumonitis from novel cancer therapies. Then, we will discuss pneumonitis from representative agents of precision cancer therapy, including mammalian target of rapamycin inhibitors, epidermal growth factor receptor inhibitors, and ICI, focusing on the incidence, risk factors, and the spectrum of CT patterns. Finally, the article will address emerging challenges in the diagnosis and monitoring of pneumonitis, including pneumonitis from combination ICI a...
Source: Seminars in Respiratory and Critical Care Medicine - October 28, 2022 Category: Respiratory Medicine Authors: Tseng, Shu-Chi Lee, Ho Yun Nishino, Mizuki Tags: Review Article Source Type: research

Acute kidney injury and electrolyte disorders in the critically ill patient with cancer
Purpose of review Patients with cancer increasingly make up a significant proportion of patients receiving care in the intensive care unit (ICU). Acute kidney injury and cancer-associated electrolyte disorders are encountered in many of these patients and can significantly impact both short-term and long-term outcomes. Recent findings Advances in chemotherapeutic regimens as well as in our understanding of cancer-associated kidney disease highlight the need for specialized knowledge of the unique causes and therapies required in this subset of critically ill patients. This is especially the case as targeted cancer the...
Source: Current Opinion in Critical Care - November 2, 2017 Category: Nursing Tags: RENAL SYSTEM: Edited by Ravindra L. Mehta Source Type: research

On the right course? A review of the quality of care provided to patients aged 24 years and under who were receiving systemic anti-cancer therapy and subsequently died or were admitted to critical care
This analysis of care delivered to children and young adults who either died or had an unexpected admission to critical care within 60 days of receiving systemic anti-cancer therapy (SACT) has shown a mixed picture of care received.
Source: Current Awareness Service for Health (CASH) - December 20, 2018 Category: Consumer Health News Source Type: news

Triage and Prognostication of Cancer Patients Admitted to the Intensive Care Unit
Cancer remains a leading cause of morbidity and mortality. Advances in cancer screening, early detection, targeted therapies, and supportive care have led to improvements in outcomes and quality of life. The rapid increase in novel cancer therapies can cause life-threatening adverse events. The need for intensive care unit (ICU) care is projected to increase. Until 2  decades ago, cancer diagnosis often precluded ICU admission. Recently, substantial cancer survival has been achieved; therefore, ICU denial is not recommended. ICU resources are limited and expensive; hence, appropriate utilization is needed. This review foc...
Source: Critical Care Clinics - October 29, 2020 Category: Intensive Care Authors: Dereddi Raja Shekar Reddy, Gregory H. Botz Source Type: research

Medical oncologists' perception of palliative care programs and the impact of name change to supportive care on communication with patients during the referral process. A qualitative study.
Abstract Objective: In a simultaneous care model, patients have concurrent access to both cancer-directed therapies and palliative care. As oncologists play a critical role in determining the need/timing of referral to palliative care programs, their understanding of the service and ability to communicate this with patients is of paramount importance. Our study aimed to examine oncologists' perceptions of the supportive care program at M.D. Anderson Cancer Center, and to determine whether renaming "palliative care" to "supportive care" influenced communication regarding referrals. Method:...
Source: Palliative and Supportive Care - January 10, 2013 Category: Palliative Care Authors: Rhondali W, Burt S, Wittenberg-Lyles E, Bruera E, Dalal S Tags: Palliat Support Care Source Type: research

Content, quality, and readability of website information on dental care for patients with cancer
Conclusions: Websites addressing dental care for patients with cancer are broad in content yet are limited in quality and are written at difficult reading levels.
Source: Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics - April 10, 2014 Category: ENT & OMF Authors: Lauren L. Patton, Stephanie F. George, Robert P. Hollowell Tags: Oral Medicine Source Type: research

Anna F. Farago, MD, PhD - The TRK to Tumor-Agnostic Care in Solid Tumors: A Pathology-Focused Guide to the Clinical Role of TRK Fusions in Personalizing Cancer Therapy
The TRK to Tumor-Agnostic Care in Solid Tumors: A Pathology-Focused Guide to the Clinical Role of TRK Fusions in Personalizing Cancer Therapy
Source: Peerview CME/CE Video Podcast - Internal Medicine International - March 6, 2019 Category: Internal Medicine Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: video

Daniel Pallin, MD, MPH - Oncologic Emergencies in the ED: Recognizing and Managing Adverse Reactions Associated With Modern Cancer Therapies —Essential Guidance for Emergency Medicine Specialists
Oncologic Emergencies in the ED: Recognizing and Managing Adverse Reactions Associated With Modern Cancer Therapies—Essential Guidance for Emergency Medicine Specialists
Source: PeerView CME/CE Audio Podcast - Primary Care - February 2, 2018 Category: Primary Care Authors: PVI, PeerView Institute for Medical Education Tags: Science, Medicine Source Type: podcasts

Turgut Ozal University Faculty of Medicine 6th International Student Congress.
Abstract Turgut Ozal University Scientific Research Committee (TOBAT) was established in Turgut Ozal University Faculty of Medicine in 2009 to encourage young medical students and scientists to carry out novel scientific research in addition to their medical education in order to 1) establish a platform of informing the latest advancements in science, 2) present this work to colleagues and 3) meet and interact with their peers within the international medical and scientific community. Our committee annually organizes Turkey's most highly-qualified medical student congress with the highest number of presenters and ...
Source: Clinical and Investigative Medicine - August 21, 2015 Category: Biomedical Science Authors: Faculty Of Medicine 6th International Student Congress TO Tags: Clin Invest Med Source Type: research

Increasing Access to Care for Chronic Myeloid Leukemia Patients: Assessment of a Scaling-up Program.
Conclusions . Positive institutional changes that improve care of CML/GIST patients arose from GIPAP. Some of these changes may strengthen institutions' capacity to treat other diseases as well. The GIPAP model could be deployed to improve access to care for patients with other chronic diseases. PMID: 24185146 [PubMed - in process]
Source: Journal of Health Care for the Poor and Underserved - November 8, 2013 Category: Global & Universal Authors: Ladner J, Tekinturhan E, Tavolacci MP, Audureau E, Saba J Tags: J Health Care Poor Underserved Source Type: research

Effect of a spiritual care training program for staff on patient outcomes.
Abstract OBJECTIVE: Physicians and nurses do not assess spirituality routinely, even though spiritual care is a vital part of palliative care for patients with an advanced serious illness. The aim of our study was to determine whether a training program for healthcare professionals on spirituality and the taking of a spiritual history would result in improved patient quality of life (QoL) and spiritual well-being. METHOD: This was a cluster-controlled trial of a spiritual care training program for palliative care doctors and nurses. Three of seven clinical teams (clusters) received the intervention, while the...
Source: Palliative and Supportive Care - November 28, 2016 Category: Palliative Care Authors: Yang GM, Tan YY, Cheung YB, Lye WK, Lim SH, Ng WR, Puchalski C, Neo PS Tags: Palliat Support Care Source Type: research